From AHA 2025 in New Orleans, Dr. Ahmad Masri provides an important update on precision medicine in obstructive hypertrophic cardiomyopathy (oHCM) care. Cardiac myosin inhibitors are ushering in a new treatment era for patients with oHCM, and Dr. Masri breaks down how this evolving therapeutic class targets the underlying hypercontractility driving left ventricular outflow tract obstruction. This marks a paradigm shift from symptomatic management and surgical intervention to a more precise, disease-modifying approach that reduces obstruction, improves symptoms, and enhances patients’ quality of life.
Precision Medicine in Obstructive HCM Care: The Promise of Cardiac Myosin Inhibitors

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Precision Medicine in Obstructive HCM Care: The Promise of Cardiac Myosin Inhibitors
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Overview
From AHA 2025 in New Orleans, Dr. Ahmad Masri provides an important update on precision medicine in obstructive hypertrophic cardiomyopathy (oHCM) care. Cardiac myosin inhibitors are ushering in a new treatment era for patients with oHCM, and Dr. Masri breaks down how this evolving therapeutic class targets the underlying hypercontractility driving left ventricular outflow tract obstruction. This marks a paradigm shift from symptomatic management and surgical intervention to a more precise, disease-modifying approach that reduces obstruction, improves symptoms, and enhances patients’ quality of life.
Provider(s)/Educational Partner(s)

videoADAPT AF-DES: Antithrombotic Strategies Beyond 12 Months for Patients With AF Treated With Drug-Eluting-Stents
Show more
videoOCEAN Trial at AHA 2025: Anticoagulation After AF Ablation in High-Risk Patients
Show more
videoDECAF Trial: Does Eliminating Coffee Reduce Atrial Fibrillation Recurrence in Symptomatic Patients?
Show more
videoPOLY HF Trial: A Polypill Strategy for Heart Failure With Reduced Ejection Fraction (HFrEF)
Show more
videoDARE AF Trial: Dapagliflozin to Reduce AF Burden After Catheter Ablation in Patients Without Diabetes or Heart Failure
Show more
videoThe Lp(a)-Lowering Landscape: Navigating Current and Future Therapeutic Options
Show more
videoThe LDL-C-Lowering Landscape: Navigating Current and Future Therapeutic Options
Show more
videoHighlights of the Latest Hypertension Guidelines
Show more
videoClinical Perspective on New Therapies in Resistant Hypertension
Show more
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